Articles Tagged With:
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Consensus Panel Offers Guidance for Pediatric Mental Health Boarding
EDs nationwide continue to see pediatric mental health patients boarded in the department for long periods while awaiting inpatient bed placement. A group of 23 experts from 17 health systems sought to identify what EDs are facing, to learn how departments are handling the problem, and to offer recommendations to standardize practices.
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Boarded Mental Health Patients: Out of Sight, Out of Mind
Many EDs routinely board mental health patients for days on end, awaiting transfer to a mental health facility. An expert offers tips to help emergency medicine providers alleviate safety and medical/legal risks.
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Disease-Modifying Therapy After Natalizumab Discontinuation in Patients with Relapsing Multiple Sclerosis
In this retrospective cohort study, the investigators found that, when compared to fingolimod and dimethyl fumarate, ocrelizumab use was associated with significantly lower annualized relapse rate and treatment discontinuation. There were no significant differences in outcomes between fingolimod and dimethyl fumarate use. Ocrelizumab use was associated with a lower rate of disability accumulation when compared to fingolimod.
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Treatment of Psychotic Symptoms in Alzheimer’s Disease
In a meta-analysis of several large treatment trials of patients with Alzheimer’s disease, Parkinson’s disease, and dementia with Lewy bodies, cholinesterase inhibitors demonstrated a small but statistically significant benefit in reducing psychotic symptoms.
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Antidepressants for Chronic Pain: Do They Work?
Antidepressant medications have been widely used for treating a variety of chronic pain disorders but strong evidence to support their efficacy is lacking. Some patients may respond, but available data do not help us to determine which agents may be helpful in a specific type of chronic pain condition.
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Celery Seed-Derived Compound: A Legitimate Neuroprotectant for Acute Ischemic Stroke?
A Phase III double-blind, placebo-controlled, randomized controlled trial suggests that early administration of DL-3-n-butylphthalide, when given adjunctively to thrombolysis or endovascular therapy, improves functional outcomes in patients with acute ischemic stroke. Statistically significant results of well-designed analyses are tantalizing, but confidence in the findings is tempered by a lack of generalizability, an unclear mechanism of action, and trial design irregularities.
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Brain Atrophy and Type 1 Diabetes
In a long-term longitudinal study of people with type 1 diabetes, excessive brain atrophy and cognitive dysfunction were noted compared to healthy controls. The investigators calculated that type 1 diabetes resulted in six years of accelerated brain aging and brain atrophy that was separate and distinct from Alzheimer’s disease.
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Delivering an Evidence-Based Intervention to Latino Patients with Alcohol Use Disorders
Automated tools offer a viable approach for addressing alcohol-related healthcare disparities in busy emergency departments.
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Infectious Disease Alert Updates
Transcatheter Aortic Valve Endocarditis; Daptomycin-Associated Eosinophilic Pneumonia: The Lyon Algorithm
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Leprosy Cases with Possible Acquisition in the United States
Six patients in California were found to have leprosy in the absence of a known exposure.